教师基本信息
一、 基本情况：
黄贝，男，1982年12月出生，副教授，硕士生导师。2012年毕业于中国科学院水生生物研究所，获博士学位。福建省杰出青年基金获得者。
Email: huangbei@jmu.edu.cn
通讯地址：福建省厦门市集美区印斗路43号 集美大学mobile28-365365。邮编：361021
二、 主要研究方向：
水产动物免疫学，水产动物疾病防控
三、 主持在研项目：
1）国家自然科学基金：“鱼类特有的干扰素调节因子11介导的免疫应答的机制”课题号：31402329
2）福建省杰出青年基金：“IRF10对鱼类抗病毒免疫应答精细调控的分子机制” 课题号：2016J06008
2）福建省自然科学基金：“鱼类特有的Toll样受体21基因的表达及功能的研究” 课题号：2014J05042
3）集美大学科研启动金：“日本鳗鲡gamma干扰素的克隆及表达分析” 课题号： ZQ2013015
4）国家海洋局海洋生物遗传资源重点实验室开放课题：“稳定表达鳗鲡TLR21基因细胞系的构建” 课题号：201406270002
5）淡水生态与生物技术国家重点实验室开放课题：“鱼类特有的Toll样受体20基因的免疫功能研究” 课题号：2014FB03
四、 代表论著
1. Huang WS, Zhu MH, Chen S, Wang ZX, Liang Y, Huang B, Nie P. Molecular cloning and expression analysis of a fish specific interferon regulatory factor, IRF11, in orange spotted grouper, Epinephelus coioides. Fish & shellfish immunology. 2017 Jan;60:368-379.
2. Huang B, Jia QQ, Liang Y, Huang WS, Nie P. Interferon regulatory factor 10 (IRF10): Cloning in orange spotted grouper, Epinephelus coioides, and evolutionary analysis in vertebrates. Fish & shellfish immunology. 2015 46(2):669-77.
3. Huang B, Huang W SH, Nie P. Cloning and expression analyses of interferon regulatory factor (IRF) 3 and 7 genes in European eel, Anguilla anguilla with the identification of genes involved in IFN production. Fish & Shellfish Immunology. 2014 37(2):239-247
4. Huang B, Huang W SH, Nie P. Characterization of four Mx isoforms in the European eel, Anguilla anguilla. Fish & Shellfish Immunology. 2013 35(3):1048-1054.
5. Huang B, Qi Z T, Xu Z, Nie P. Global characterization of interferon regulatory factor (IRF) genes in vertebrates: Glimpse of the diversification in evolution. BMC immunology. 2010 11, 22.
6. Gan Z, Chen SN, Huang B, Hou J, Nie P. Intronless and intron-containing type I IFN genes coexist in amphibian Xenopus tropicalis: Insights into the origin and evolution of type I IFNs in vertebrates. Developmental and Comparative immunology . 2017 Feb;67:166-176.
7. Chen SN, Zhang XW, Li L, Ruan BY, Huang B, Huang WS, Zou PF, Fu JP, Zhao LJ, Li N, Nie P. Evolution of IFN-λ in tetrapod vertebrates and its functional characterization in green anole lizard (Anolis carolinensis). Developmental and Comparative immunology. 2016 Aug;61:208-24
8. Huang WS, Duan LP, Huang B, Wang KJ, Zhang CL, Jia QQ, Nie P, Wang T.Macrophage migration inhibitory factor (MIF) family in arthropods: Cloning and expression analysis of two MIF and one D-dopachrome tautomerase (DDT) homologues in mud crabs, Scylla paramamosain. Fish & shellfish immunology. 2016 Mar;50:142-9.
9. Li N, Qin T, Zhang XL, Huang B, Liu ZX, Xie HX, et al. Gene Deletion Strategy To Examine the Involvement of the Two Chondroitin Lyases in Flavobacterium columnare Virulence. Applied and environmental microbiology. 2015.
10. Wu N, Zhang XY, Huang B, Zhang N, Zhang XJ, Guo X, et al. Investigating the potential immune role of fish NCAMs: Molecular cloning and expression analysis in mandarin fish. Fish & shellfish immunology. 2015 46(2):765-77.
11. Huang WS, Duan LP, Huang B, Zhou LH, Liang Y, Tu CL, et al. Identification of three IFN-gamma inducible lysosomal thiol reductase (GILT)-like genes in mud crab Scylla paramamosain with distinct gene organizations and patterns of expression. Gene. 2015 570(1):78-88.
12. Chang MX, Zou J, Nie P, Huang B, Yu Z, Collet B, Secombes CJ. Intracellular interferons in fish: a unique means to combat viral infection. PLoS Pathogens 2013 9(11): e1003736.
13. Fu JP, Chen SN, Zou PF, Huang B, Guo Z, Zeng LB, Qin QW, Nie P. IFN-γ in turtle: Conservation in sequence and signalling and role in inhibiting iridovirus replication in Chinese soft-shelled turtle Pelodiscus sinensis. Developmental and Comparative immunology. 2013 43(1):87-95.
14. Chen SN, Huang B, Zhang XW, Li Y, Zhao LJ, Li N, Gao Q, Nie P. IFN-γ and its receptors in a reptile reveal the evolutionary conservation of type II IFNs in vertebrates. Developmental and comparative immunology. 2013 41(4):587-596.
15. Wang G, Li J, Zou P, Xie H, Huang B, Nie P, Chang M. Expression pattern, promoter activity and bactericidal property of beta-defensin from the mandarin fish Siniperca chuatsi. Fish & Shellfish Immunology. 2012 33(3):522-531.
16. Zhang SH, Zhu DD, Chang MX, Zhao QP, Jiao R, Huang B, et al. Three goose-type lysozymes in the gastropod Oncomelania hupensis: cDNA sequences and lytic activity of recombinant proteins. Developmental and comparative immunology. 2012 36(1):241-246.
17. Zhang J, Zou H, Wang L F, Huang B, Li N, Wang G T, Nie P. Construction of two selectable markers for integrative/conjugative plasmids in Flavobacterium columnare. Chinese Journal of Oceanology and Limnology. 2012 30(2): 269-278.
18. Li N, Zhang L Q, Zhang J, Liu Z X, Huang B, Zhang S H, Nie P. Type I restriction-modification system and its resistance in electroporation efficiency in Flavobacterium columnare. Veterinary Microbiology. 2012 160(1-2): 61-68.
19. Wei YC, Pan TS, Chang MX, Huang B, Xu Z, Luo TR, Nie P. Cloning and expression of Toll-like receptors 1 and 2 from a teleost fish, the orange-spotted grouper Epinephelus coioides. Veterinary Immunology and Immunopathology. 2011 141(3-4): 173-182.
20. Qi ZT, Zhang QH, Wang ZS, Wang AM, Huang B, Chang MX, Nie PCloning and expression analysis of a long type peptidoglycan recognition protein (PGRP-L) from Xenopus tropicalis. Zoological research. 2011 32(4):371-378
21 Xu QQ, Chang MX, Xiao FS, Huang B, Nie P. The gene and virus-induced expression of IRF-5 in grass carp Ctenopharyngodon idella. Veterinary immunology and immunopathology. 2010 134(3-4):269-278.
22. Xu Z, Chang MX, Qi ZT, Huang B, Nie P. Immunoglobulin joining (J) chain and its expression in the Chinese soft-shelled turtle (Pelodiscus sinensis). Veterinary immunology and immunopathology. 2009 131(3-4):268-272.
23. 黄贝、陈善楠、黄文树、聂品，斜带石斑鱼IFN-γ基因的克隆与表达分析，中国水产科学，2013 第20卷， 第2期， 269-275页.
24. 黄贝、陈善楠、徐镇、聂品， 斜带石斑鱼IgM、IgZ和IgD重链基因的克隆，水产学报，2012 第36卷， 第7期， 1000-1010页.
25. 段利朋、黄贝、周立红、梁英、聂 品、黄文树，拟穴青蟹两种新C-型凝集素基因的克隆与表达分析，水生生物学报，2015, 第39卷，第2期，321-330页.
26. 王资生、齐志涛、黄贝、张启焕、仇明、邵荣，梭鱼白细胞介素-22原核表达及活性蛋白的制备，华中农业大学学报，2012，第31卷， 第6期，752-775页。
27．齐志涛、张启焕、黄贝、王资生、仇明、黄金田、许伟、王爱民，非洲爪蟾BAFF及其信号通路相关基因的比较生物信息学分析，生物技术，2011，第6期
28. 齐志涛、高谦、张启焕、黄贝、王爱民、王资生、聂品， 非洲爪蟾干扰素-λ1基因的原核表达， 水生生物学报， 2011 第35卷， 第6期， 1060-1063页.
29. 齐志涛、高谦、黄贝、昌鸣先、聂品，非洲爪蟾短型肽聚糖识别蛋白基因的克隆与鉴定，水生生物学报，2010，第34卷， 第5期，922-926页。
30. 齐志涛、张启焕、王资生、许伟、黄贝、王爱民，非洲爪蟾IL-6基因的克隆及生物信息学分析，生物技术通报，2010， 第11期，129-133页。