基本信息
方铭,男,集美大学闽江学者特聘教授(2017),入选2018厦门市双百计划
出生日期:1979年11月
研究方向:统计基因组、水生动物遗传育种
Email: fangming618@126.com
通讯地址:厦门市集美区印斗路43号,集美大学mobile28-365365(361021)
教育/工作经历
2017.12-至今,集美大学,mobile28-365365,教授
2016.8-至今,华大基因公司,技术顾问
2011.12-2017.12,黑龙江八一农垦大学,生命学院,副教授
2008.9-2011.11,黑龙江八一农垦大学,生命学院,讲师
2005.8-2008.8,黑龙江八一农垦大学,生命学院,助教
教学情况:
实验设计与统计分析
统计基因组
主持科研项目:
1.国家自然科学基金面上项目,31672399,利用高通量测序数据检测顺式作用遗传变异的新方法及其应用,2017/01-2020/12,64万,在研,主持
2.国家自然科学基金青年科学基金项目,31001001,畜禽系谱群体重要经济性状位点的高效力精细定位方法,2011/01-2013/12,19万,已结题,主持
3.黑龙江省教育厅新世纪优秀人才支持计划,1253—NCET—001,畜禽全基因组育种值预测的高维分析方法,2013/06-2017/06,20万,结题,主持
主要论著(#同等第一,*通讯作者 ):
1. Hailiang Huang1#, Ming Fang1#, Luke Jostins1#, Masa U. Mirkov, International the IBD Genetics Consortium, Michel Georges, Jeffrey C. Barret and Mark J. Daly. Fine-mapping inflammatory bowel disease loci to single-variant resolution. 2017, Nature, 13;547(7662):173-178.
2. Jun-Feng Gao, Yuan Gao, Jian-Hua Qiu, Qiao-cheng Chang, Yan Zhang, Ming Fang*, Chun-Ren Wang*. De novo assembly and functional annotations of the transcriptome of Metorchis orientalis (trematoda: Opisthorchiidae). 2018. Experimental Parasitology.
3. Changliang Qiu#, Linsong Dong#, Shijun Xiao, Shuangbin Xu, Ming Fang, Zhiyong Wang. Genetic parameters estimation of Nine Quantitative Traits by a marker-based method in Large Yellow Croaker, Larimichthys crocea (Rechardson). 2017. Aquaculture Research.
4. Yuxue Gao, Linsong Dong, shuangbin Xu, Shijun Xiao, Ming Fang, Zhiyong Wang*. Genome-wide association study using single SNP analysis and Bayesian method for swim bladder index and gonadosomatic index in large yellow croaker. 2017. Aquaculture.
5. Linsong Dong; Ming Fang, Zhiyong Wang. Prediction of genomic breeding values using new computing strategies for the implementation of MixP. 2017. Scientific Reports.
6. Jun-Feng Gao, Guo-Hua Liu, Hong Duan, Yuan Gao, Yan Zhang, Qiao-Cheng Chang, Ming Fang, Chun-Ren Wang. Complete mitochondrial genomes of Triodontophorus serratus and Triodontophorus nipponicus, and their comparison with Triodontophorus brevicauda.. 2017. Experimental Parasitology.
7. Ming Fang, Michel Georges*, BayesFM: a software program to fine-map multiple causative variants in GWAS identified risk loci. 2016, Biorxiv
8. Yang Deguang#, Han Shanshan#, Jiang Dan#, Yang Runqing and Ming Fang*. Inference of posterior inclusion probability of QTLs in Bayesian shrinkage analysis. Genet. Res. 2015. doi:10.1017/S001667231500001.
9. Jiang Dan, Ma Guoda, Yang Runqing, Li Kesen *, and Ming Fang*. Bayesian model selection for multiple QTLs mapping combining linkage disequilibrium and linkage. Genet. Res. 2014. doi: 10.1017/S0016672314000135.
10. Ming Fang*, Fu Weixuan, Zhang Qin*, Ding Xiangdong, Sun Dongxiao*. A Multiple-SNP Approach for Genome-Wide Association Study of Milk Production Traits in Chinese Holstein Cattle. PLOS ONE, 2014, 9(8):e99544.
11. Dan Jiang, Yanli Wu, Jiahan li, Yang Wu, Ming Fang and Runqing Yang. Cox regression model for dissecting genetic architecture of survival time. Genomics, 2014, 104 (6):472-476.
12. Xiaoping Wu#, Ming Fang#, Lin Liu, Sheng Wang, Jianfeng Liu, Xiangdong Ding, Shengli Zhang, Qin Zhang, Yuan Zhang, Lv Qiao, Mogens Sand Lund, Guosheng Su, Dongxiao Sun*. Genome wide association studies for body conformation traits in the Chinese Holstein cattle population. BMC Genomics, 2013, 14:897.
13. Ming Fang*. A fast expectation-maximum algorithm for fine-scale QTL mapping. Theoretical and Applied Genetics, 2012,125:1727-1734.
14. Ming Fang*, Dan Jiang, Dandan Li, Runqing Yang. Improved LASSO priors for shrinkage QTL mapping. Theoretical and Applied Genetics, 2012, 124(7):1315-24.
15. Xiaojing Zhou, Ming Fang, Jiahan Li, Daniel R Prows, Runqing Yang. Characterization of genomic imprinting effects and patterns with parametric accelerated failure time model. Molecular Genetics and Genome, 2012, 287(1):67-7.
16. Ming Fang#, Jianfeng Liu#, Qin Zhang* and Dongxiao Sun*. QTL Mapping in Outbred Half-sib Families Using Bayesian Model Selection. Heredity, 2011, 107, 265-276. (SCI: IF=3.8; 4 cited)
17. Ming Fang*. Bayesian shrinkage mapping of quantitative trait loci in variance component models. BMC Genetics, 2010, 11(1):1-10.
18. Ming Fang*, Shengcai Liu, Dan Jiang, Bayesian composite model space approach for mapping quantitative trait loci in variance component model. Behav Genet, 2009, 39: 337-346.
19. Gao H, Ming Fang, Liu JF, Zhang Q*, Bayesian shrinkage mapping for multiple QTL in half-sib families. Heredity, 2009, 103(5): 368-376.
20. Ming Fang*, Dan Jiang, Lijun Pu, Huijiang Gao, Peng Ji, Hongyi Wang, et al., Multitrait analysis of quantitative trait loci using Bayesian composite space approach. BMC Genetics, 2008, 9:48.
21. Ming Fang*, Dan Jiang, Huijiang Gao, Dongxiao Sun, RQ Yang, Qin Zhang, A new Bayesian automatic model selection approach for mapping quantitative trait loci under variance component model. Genetica, 2008, 135(3): 429-439.
22. Ming Fang*, Dan Jiang, Xu Chen, Lijun Pu, Shengcai Liu, Bayesian analysis of genetic architecture of quantitative trait using data of crosses of multiple inbred lines. Genetica, 2008, 134(3): 367-375.
23. Runqing Yang*, Ming Fang, Mapping quantitative trait loci in line cross with repeat records. BMC Genetics, 2007, 8: 47.
24.李勇#, 苗泽圃#,蒙小云#, 杨漫漫, 魏强, 郭笑峰, 郑华*, 方铭* RAD-seq技术在大白猪繁殖性状基因组选择上的应用. 农业生物技术学报,2017, 25(9):1508-1515